Short-Term Moderately Elevated Intraocular Pressure Is Associated With Elevated Scotopic Electroretinogram Responses
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چکیده
منابع مشابه
Short-Term Moderately Elevated Intraocular Pressure Is Associated With Elevated Scotopic Electroretinogram Responses
PURPOSE Moderately elevated intraocular pressure (IOP) is a risk factor for open-angle glaucoma. Some patients suffer glaucoma despite clinically measured normal IOPs. Fluctuations in IOP may have a significant role since IOPs are higher during sleep and inversion activities. Controlled transient elevations of IOPs in rats over time lead to optic nerve structural changes that are similar to the...
متن کاملEarly glial responses after acute elevated intraocular pressure in rats.
PURPOSE To study the responses of glial cells to a short-term elevation in intraocular pressure (IOP) in rats. METHODS Adult Sprague-Dawley albino rats, 45 to 55 days old, were given India ink intracamerally. After 7 days, 200 spots of laser burn over 360 degrees were delivered by an Argon laser (620-637 nm; 200 mW; 200 mm; 0.2 seconds) aimed at the ink deposits in the trabecular meshwork. IO...
متن کاملThe electroretinogram and choroidal PO2 in the cat during elevated intraocular pressure.
The effects of elevated intraocular pressure (IOP) on the dark-adapted standing potential (SP), b- and c-waves of the electroretinogram (ERG) and choroidal PO2 of the intact cat eye were studied. During pressure elevation the SP increased, c-wave amplitude increased and the b-wave decreased, with the SP and c-wave being considerably more sensitive to pressure elevation. Inspiration of 100% O2 r...
متن کاملReduction on OFF-responses of Electroretinogram in Monkeys with Long-term High Intraocular Pressure
BACKGROUND There are ON- and OFF-pathways in the normal vertebrate retina. Short- and long-flash electroretinogram (ERG) are suitable methods to observe the function of ON- and OFF-pathways in vivo, respectively. It is clear that high intraocular pressure (IOP) might cause dysfunction of cone-dominated photopic negative response (PhNR) in monkeys with high IOP in ON-pathway. However, whether co...
متن کاملProteomic analysis of elevated intraocular pressure with retinal detachment
PURPOSE To report a case of elevated intraocular pressure with retinal detachment. OBSERVATIONS Liquid chromatography and tandem mass spectrometry was performed on the patient aqueous biopsy. Protein levels were analyzed with 1-way analysis of variance (ANOVA) and unbiased clustering. High levels of rod outer segment proteins were not detected, suggesting that this was not a case of Schwartz-...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2016
ISSN: 1552-5783
DOI: 10.1167/iovs.15-18770